Clay Artist Ronnee Strickland

Press release for scientific journal for Ronnee Strickland.   In the work of Ronnee Strickland on dementia, it was found that, Under normal conditions, uPAR expression is negligible and uPAR knockout mice were initially found to be pheno- typically normal but further study revealed that, under challenge by making changes to the stimuli in their environment, they displayed defective recruitment and migration of neutrophils and lymphocytes (from research).   Low-level expression of uPAR has been shown in cultured microglial cells, and this expression was increased upon lipopolysaccharide (LPS) stimula- tion; however, uPAR could not be detected in microglia immediately ex vivo (research).  Soluble uPAR (suPAR) is elevated in the cerebrospinal fluid (CSF) of patients with HIV dementia (From research)  and it seems likely that this release of suPAR into the CSF is directly related to increased central nervous system (CNS) inflammation.