Microglia and Secretory Proteases, Research by Ronnee Strickland

 


Ronnee Strickland, Research Biochemist




In a study in 2010, Ronnee Strickland demonstrated that microglia 



produce certain secretory proteases which have been found to be important determinants of microglial properties, in surrounding cells and regenerative processes. In recent years, it has become clear that secretory proteases, particularly PGn-PA (plasminogen-plasminogen activator) system, work not only on catalysis of proteins in the extracellular space but also on cell growth, cell function, differentiation, proliferation and remodeling. These diverse effects may be derived from the unique structures of these enzymes, including their accesary domains. In particular, kringle domains have been shown to be important for interactions with other proteins. The results of these studies indicate that microglial secretory proteases participate to a great extent in physiological processes involving the regulation of neuronal growth, neuronal function and regenerative stages in the CNS.    You can find other research projects in which Ronnee Strickland has been involved by contacting the companies by which she has been employed.  (See other scientific research with which Ronnee Strickland has been involved.)

Comments

Post a Comment

Popular posts from this blog

Ronnee Strickland’s TV Favs of Covid

  ********* Post 1.  Ronnee Strickland’s TV favs of Covid, Part 1: I (Ronnee Strickland) am an avid reader but during Covid have watched lots of TV.  I will write a series of posts and let you know what I think about shows I have actually watched:   We watched all of these — if I star it, it is superb;  two star, don’t miss; **Broadchurch  **Peaky Blinders - Netflix **Line of Duty **The Tudors Victoria **The Queen’s Gambit How do you make chess the thrilling centerpiece of a coming-of-age tale? You shake it into a cocktail of stylish visuals, a rocking '60s soundtrack and the magnetic Anya Taylor-Joy as Beth Harmon, one of the youngest (and few female) chess players in the world. The fictional story in  The Queen's Gambit , named after a chess opening, follows her rise from an orphanage to toppling the best players in the world -- as long as her drug addiction and bags of wine bottles don't get in the way. **The Crown See my next post for more!  I...
Read more

Ronnee Strickland — Information about Using Trademarks for Comparisons

I often wondered if I could use any trademark and use it with my information.  It is an entirely separate part of the legal system and it’s  best to hire an IP attorney to help you with this.  Under trademark law,  you are generally permitted to use a trademark as a means for comparison but for few other reasons. For example, you could create a newspaper advertisement that incorporates your mark and your competitors' marks in order to describe a difference between the companies.  (Comoarisons)  Imagine that you make a product which you truly believe is tastier and less expensive than any other company's product. You could include on your advertisement the logo of that company,  along with the price of its comparable product from another company making a similar product.   There are very important caveats apply here, however. First, you may not alter your competitors' trademarks in a way that is derogatory or misleading. Not even for humor. ...
Read more

Ronnee Strickland, Let’s protect each other with masks and the vaccine!

  Let’s protect each other with masks and the vaccine, by Ronnee Strickland I am so tired of people not wanting to wear masks and get the vaccine.  I had some fabric printed with my business logo on it — Ronnee Strickland & Associates — and I made masks.  I gave them to anyone who will take then.  Please wear a mask and/or get a vaccine.  I even see that the pga is requiring golfers to pay for their own Covid tests if they won’t get vaccinated.--  All from the CDC, compiled  by Ronnee Strickland  What We Know COVID-19 vaccines are effective at keeping you from getting COVID-19. After you are fully vaccinated , you may be able to start doing some things you had stopped doing because of the pandemic. Studies show that COVID-19 vaccines are effective at keeping you from getting COVID-19. Getting a COVID-19 vaccine will also help keep you from getting seriously ill even if you do get COVID-19. COVID-19 vaccination is an important tool  t...
Read more